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#REDIRECT [[Potassium_iodide#Thyroid_protection_from_iodine-131_in_fission_accidents_and_emergencies]]
'''Thyrosafe''' is a [[potassium Iodide]] tablet manufactured by [[Recipharm]] AB. The manufacturer describes it as "the only FDA approved 65 mg. Potassium Iodide (KI) tablet."<ref>{{cite web|url=http://www.thyrosafe.com/|title=Why Thyrosafe Potassium Iodide?|publisher=Thyrosafe}}</ref> It is marketed in boxes of 20 x 65&nbsp;mg tablets ($11.95) to be stockpiled in the event of an emergency, such as "a nuclear terrorist attack or nuclear emission from an accident at a power plant", to be taken "just before or just after" ingestion of radioactive fallout to prevent thyroid cancer by saturating the thyroid with iodine.<ref>{{cite news |title=Residents near Fermi to get anti-radiation pills |author=Charles Slat |url=http://www.monroenews.com/apps/pbcs.dll/article?AID=/20090904/NEWS01/709049978/-1/NEWS |newspaper=Monroe News |date=September 4, 2009 |accessdate=18 December 2010}}</ref>

Similar drugs consisting of [[potassium iodide]] include Iostat, Pima, [[SSKI]], Thyro-block, ThyroShield, and Yodefan.<ref>{{cite web|url=http://www.prescriptiondrug-info.com/drugs/thyrosafe.asp|title=Thyrosafe|publisher=PrescriptionDrug-info.com}}</ref> A wide variety of potassium iodide nutritional supplements are available with comparable levels of potassium iodide at somewhat lower prices,<ref>{{cite news |title=A firm in position to profit |author=David Lazarus |url=http://articles.sfgate.com/2004-03-21/business/17417702_1_iodide-pills-power-plant-carlyle-group/2 |newspaper=[[San Francisco Chronicle]] |date=March 21, 2004 |accessdate=18 December 2010}}</ref> for example Natural Balance No-Rad tablets labelled for a 200&nbsp;mg daily dosage.<ref>{{cite web|url=http://www.vitaminproshop.com/norad.html|title=Product site}}</ref>
==Side effects==
Taken at a dose of 130&nbsp;mg daily in adults or 65&nbsp;mg in children, possible side effects include "swelling of the salivary glands, nausea, vomiting, diarrhea, stomach ache, fever, headache, metallic taste, and allergic reactions." Allergic reactions can include skin rashes, swelling of various parts of the body, fever with joint pain, trouble breathing, speaking or swallowing, wheezing or shortness of breath. Rarely it may cause overactivity, underactivity, or enlargement ([[goiter]]) of the thyroid gland. Thyroid overactivity can cause irregular heartbeat and chest pain.<ref>{{cite web|url=http://www.odh.ohio.gov/ASSETS/830942CF21494D0D90FD465FDE2F8682/ThyroSafe%20Leaflet.pdf|title=Consumer package insert}}</ref>

==History==
Thyrosafe was officially approved for use in the United States in September of 2002.<ref>{{cite news |title=The FDA and the fight against terrorism |author= |url=http://goliath.ecnext.com/coms2/gi_0199-4435970/The-FDA-and-the-fight.html |newspaper=[[FDA Consumer]] |date=January 1, 2004 |accessdate=18 December 2010}}</ref>

During the Potassium Iodide Initiative in [[Pennsylvania]] in 2008, tablets of thyrosafe were given out to "residents living within 10 miles of Limerick Nuclear Generating Station" in order to protect them "in the event radioactive iodine is released from the nuclear power plant."<ref>{{cite news |title=Dozens show up for anti-nuke pills |author=Dennis J. Wright |url=http://www.thereporteronline.com/articles/2009/09/02/news/doc4a9eb3b21563b222678568.txt?viewmode=fullstory |newspaper=[[The Reporter (Lansdale)|The Reporter]] |date=September 2, 2009 |accessdate=18 December 2010}}</ref> Such tablets were also given out in 2003 in [[York County, South Carolina]] for the residents living near the state's three "commercial nuclear reactors", along with one in the neighboring state of Georgia.<ref>{{cite news |title=York County to distribute anti-radiation pills |author=Caroline Brustad |url=http://pqasb.pqarchiver.com/heraldonline/access/330552101.html?dids=330552101:330552101&FMT=ABS&FMTS=ABS:FT&type=current&date=Apr+26%2C+2003&author=Caroline+Brustad+%2F+++The+Herald&pub=Herald+Online&desc=York+County+to+distribute+anti-radiation+pills&pqatl=google |newspaper=[[The Herald (Rock Hill)|The Herald]] |date=April 26, 2003 |accessdate=18 December 2010}}</ref>

In December of 2010, due to its production of Thyrosafe tablets, Recipharm AB's production facility in Sweden was included in the secret U.S. 2008 [[Critical Foreign Dependencies Initiative]] list, later leaked to Wikileaks and widely publicized.<ref>{{cite web|url=http://cryptome.org/0003/ci-kr-spy.htm|title=REQUEST FOR INFORMATION:CRITICAL FOREIGN DEPENDENCIES|date=2009-02|publisher=Cryptome}}</ref>

== References ==
<references />






{{pharmacy-stub}}
[[Category:Drugs]]

Revision as of 05:21, 18 December 2010

Thyrosafe is a potassium Iodide tablet manufactured by Recipharm AB. The manufacturer describes it as "the only FDA approved 65 mg. Potassium Iodide (KI) tablet."[1] It is marketed in boxes of 20 x 65 mg tablets ($11.95) to be stockpiled in the event of an emergency, such as "a nuclear terrorist attack or nuclear emission from an accident at a power plant", to be taken "just before or just after" ingestion of radioactive fallout to prevent thyroid cancer by saturating the thyroid with iodine.[2]

Similar drugs consisting of potassium iodide include Iostat, Pima, SSKI, Thyro-block, ThyroShield, and Yodefan.[3] A wide variety of potassium iodide nutritional supplements are available with comparable levels of potassium iodide at somewhat lower prices,[4] for example Natural Balance No-Rad tablets labelled for a 200 mg daily dosage.[5]

Side effects

Taken at a dose of 130 mg daily in adults or 65 mg in children, possible side effects include "swelling of the salivary glands, nausea, vomiting, diarrhea, stomach ache, fever, headache, metallic taste, and allergic reactions." Allergic reactions can include skin rashes, swelling of various parts of the body, fever with joint pain, trouble breathing, speaking or swallowing, wheezing or shortness of breath. Rarely it may cause overactivity, underactivity, or enlargement (goiter) of the thyroid gland. Thyroid overactivity can cause irregular heartbeat and chest pain.[6]

History

Thyrosafe was officially approved for use in the United States in September of 2002.[7]

During the Potassium Iodide Initiative in Pennsylvania in 2008, tablets of thyrosafe were given out to "residents living within 10 miles of Limerick Nuclear Generating Station" in order to protect them "in the event radioactive iodine is released from the nuclear power plant."[8] Such tablets were also given out in 2003 in York County, South Carolina for the residents living near the state's three "commercial nuclear reactors", along with one in the neighboring state of Georgia.[9]

In December of 2010, due to its production of Thyrosafe tablets, Recipharm AB's production facility in Sweden was included in the secret U.S. 2008 Critical Foreign Dependencies Initiative list, later leaked to Wikileaks and widely publicized.[10]

References

  1. ^ "Why Thyrosafe Potassium Iodide?". Thyrosafe.
  2. ^ Charles Slat (September 4, 2009). "Residents near Fermi to get anti-radiation pills". Monroe News. Retrieved 18 December 2010.
  3. ^ "Thyrosafe". PrescriptionDrug-info.com.
  4. ^ David Lazarus (March 21, 2004). "A firm in position to profit". San Francisco Chronicle. Retrieved 18 December 2010.
  5. ^ "Product site".
  6. ^ "Consumer package insert" (PDF).
  7. ^ "The FDA and the fight against terrorism". FDA Consumer. January 1, 2004. Retrieved 18 December 2010.
  8. ^ Dennis J. Wright (September 2, 2009). "Dozens show up for anti-nuke pills". The Reporter. Retrieved 18 December 2010.
  9. ^ Caroline Brustad (April 26, 2003). "York County to distribute anti-radiation pills". The Herald. Retrieved 18 December 2010.
  10. ^ "REQUEST FOR INFORMATION:CRITICAL FOREIGN DEPENDENCIES". Cryptome. 2009-02. {{cite web}}: Check date values in: |date= (help)